Search
  • Miriam Green

Music, Here and Now


Our family is part of a global phenomenon in current medical developments: Alzheimer’s is on the rise. What we experience on a daily basis is multiplied millions of times over in other homes, other families. And it is only going to get worse.


“Worldwide, at least 50 million people are believed to be living with Alzheimer's disease or other dementias. If breakthroughs are not discovered, rates could exceed 152 million by 2050,” states one fact sheet.


It is hard to focus on what’s happening in the scientific world when you’re mired in this disease. Each visit to Mom reminds me that we experience Alzheimer’s in an individualized, unique, and often lonely encounter.


When I raise my head from beyond the small interactions with Mom, I am awed to discover that there have been many recent promising studies on understanding the origins of dementia and in creating possible treatment methods. In Israel, where I live, there are constant news reports of scientific discovery. This past November, in honor of Alzheimer’s Awareness Month, an article on the Israel21c website highlighted ten new technologies that may advance preventing, diagnosing and treating this progressive and incurable brain disorder.


Here’s one that I particularly like because it is happening at my university, Ben Gurion University of the Negev. A novel therapy introduced by BGN Technologies of Ben-Gurion University of the Negev, “hinges on the fact that a malfunctioning blood brain barrier (BBB) allows neurotoxic blood products to enter the brain and cause damage leading to neurological diseases. The lab of BGU Professor Alon Friedman discovered that treating the BBB at early stages can protect the brain and prevent disease development. Their proposed treatment would combine Memantine and Losartan, which have been shown in preclinical studies to protect the integrity of the BBB when administered together.”


In terms of early diagnosis, an artificially intelligent chatbot named “Clara” could help detect early signs of Alzheimer’s. According to Dr. Shahar Arzy, director of the computational neuropsychiatry lab at Hadassah Hebrew University Medical Center in Jerusalem, “Clara is based on a relatively recent understanding that Alzheimer’s affects the brain’s ‘orientation system’ before it affects memory. Clara asks patients questions about themselves and their relationships to people, places and events. It then compares that information to a baseline and generates a computer-based test tailored for the individual that can diagnose very early Alzheimer’s.” Clara is 95 percent accurate.


As illustrated by Clara, one of the main focuses has been to create early detection technologies that will track the subtle, mild signs of Alzheimer’s that until now could only be found in invasive brain tissue biopsies. Before there’s even a diagnosis of mild cognitive disorder—which is usually a precursor to Alzheimer’s—some of these technologies of the future can be used to counteract or halt the growth of plaques and tangles in the brain.

Unfortunately, most of these amazing ideas will not be ready in time to save my mom. They are years away from practical applications and for being tested in real-time human trials.


And so we soldier on, trying as best we can to connect with Mom in her current state. Music is still our go-to method of interacting. In fact, it’s my number one rule of thumb: when in doubt, sing. It works almost every time to distract her from bad mood swings or outrageous anger and to engage her in a positive way. It often doesn’t matter what song we sing and if I don’t know the words, we just hum instead.


Before I leave at the end of a visit, I place Mom’s headphones on her ears. These headphones have a memory card loaded with more than 300 songs that she knows and loves. Sometimes it takes a few tries for her to accept the feel of the pads on her ears. Once a song catches her attention, she starts to sing, often in a very loud voice. That’s when I know she’s transported from her often painfully small surroundings into a place that not even Alzheimer’s can destroy. It is easier for me to say goodbye to Mom when she’s serenading me, when the dance we’ve choreographed out of our visit has run its course and she is wholly engaged in song. New technologies and medicines are years away; music is here and now.




I love being challenged to make something I’ve never made before. We were invited to eat a Shabbat meal with our close friends to celebrate the return of their daughter from a long stay in Asia. SL has spent countless hours in our house and is like my second daughter. I was intrigued to hear that she’s becoming vegan since her travels. When they requested I make vegan macaroni and cheese, I gladly said yes, and got to work. It’s actually not that difficult. And though I can’t say that it tastes exactly like macaroni and cheese, it’s a finger-licking good substitute.


Vegan Mac & Cheese

The heart of this dish is the cashew cheese, a combination of raw cashews, cooked sweet potato and some spices. If you’ve never tried Brewer’s yeast, which is an ingredient used in beer making, you’ll be surprised by how “cheesy” it makes this dish taste. (I also recommend sprinkling it on your popcorn! Hat tip to Neil Churgin.)


1 500 gr / 16 oz package pasta (your choice)

4-6 quarts water (about 24 cups)

1 tsp salt

1 large sweet potato, peeled and cooked

1 cup cashews, soaked in water for 2 hours

2 Tbsp lemon juice

3-4 cloves garlic

1 Tbsp hot paprika

2 Tbsp Brewer’s yeast (optional)

2 Tbsp crispy fried onions

¼-½ cup water

Salt and pepper to taste


Directions:

  1. Set cashews to soak in a small bowl of water for two hours.

  2. Bring 4-6 quarts of water to boil in a large pot then add pasta and cook until pasta softens. Drain and set aside.

  3. Peel and chop sweet potato. Place in pan and cover with water. Bring to a boil then simmer until potato can be pierced with a knife. Drain and cool.

  4. Place softened cashews, potato, liquids and spices in a food processor. Pulse until all ingredients are blended. Add extra water if mixture is too thick.

  5. Mix cashew “cheese” with pasta, adding extra spices if so desired.

  6. Serve warm with a sprinkling of paprika, Brewer’s yeast and extra crispy onions.


#music #technologies #BGU #clara #vegan #mac&cheese #main course

0 views

© 2023 by  Memorial. Proudly created with Wix.com